A large red brick building with columns and a green lawn in front.

Clarendon County Vacations & Trips from $510

Book a Hotel + Flight or Car together to unlock savings

Your Clarendon County Vacation

Set off on your next exciting adventure with a Clarendon County vacation package, and leave knowing all the details have been taken care of. Plus with the ability to customize your escape, it'll be one you won't forget. Begin your trip to Clarendon County by spending a few days exploring Manning, one of the top cities here. Quit dreaming and get packing, because your Clarendon County vacation is just clicks away with Expedia.

Top destinations in Clarendon County

A calm lake with kayaks on the shore, surrounded by dense forest and mountains.
FlightsHotels

Manning

Manning

The Latest Clarendon County Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • A hotel room with a bed, bedside tables, a wall-mounted light, and a patterned carpet.
    Jan 15 - Jan 18

    Americas Best Value Inn Bishopville + Flight

    Bishopville
    3 nights
    2.0 star property
    7.4/10 - Good (108 reviews)
    "There was a coffee maker in the room, but no coffee or cups!"
    Reviewed October 29, 2026
    Roundtrip • New York (NYC) - Florence (FLO)
    LGA - FLO • 1 stop FLO - JFK • 1 stop
    $577
    $510
    per traveler
    found 5 hours ago
    Americas Best Value Inn Bishopville
  • A courtyard with outdoor seating, a brick building, and trees.
    Jan 15 - Jan 18

    The Inn at the Crossroads + Flight

    Lake City
    3 nights
    2.0 star property
    9.6/10 - Exceptional (1,003 reviews)
    Roundtrip • New York (NYC) - Florence (FLO)
    LGA - GSO • Nonstop GSO - LGA • Nonstop
    $819
    $648
    per traveler
    found 5 hours ago
    The Inn at the Crossroads
  • A hotel hallway with a carpeted floor, doors on both sides, and a light fixture on the ceiling.
    Jan 15 - Jan 18

    Raceway Inn + Flight

    Darlington
    3 nights
    2.5 star property
    6.0/10 - (58 reviews)
    "One of the nastiest rooms I prolly stayed in never going back"
    Reviewed October 28, 2026
    Roundtrip • New York (NYC) - Florence (FLO)
    LGA - FLO • 1 stop FLO - JFK • 1 stop
    $1,306
    $1,132
    per traveler
    found 5 hours ago
    Raceway Inn
  • An outdoor patio with wicker furniture, a fire feature, and string lights.
    Jan 17 - Jan 20

    The Mantissa Hotel + Flight

    Hartsville
    3 nights
    3.0 star property
    9.2/10 - Wonderful (317 reviews)
    Roundtrip • New York (EWR) - Florence (FLO)
    EWR - MYR • 1 stop MYR - EWR • 1 stop
    $643
    $580
    per traveler
    found 6 hours ago
    The Mantissa Hotel
  • A Holiday Inn Express & Suites hotel with a covered entrance, multiple windows, and a parking lot.
    Jan 15 - Jan 18

    Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG + Flight

    Florence
    3 nights
    2.5 star property
    8.6/10 - Excellent (1,000 reviews)
    Roundtrip • New York (NYC) - Florence (FLO)
    LGA - FLO • 1 stop FLO - JFK • 1 stop
    $630
    $578
    per traveler
    found 5 hours ago
    Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Discover the most popular places to visit in Clarendon County

A flooded area with trees standing in water.

Santee National Wildlife Refuge

8.2/10 (105 reviews)
You can take time to visit Santee National Wildlife Refuge during your travels to Summerton. While you're here, you can savor the top-notch restaurants.
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Clarendon County Hotel Deals

A hotel room with two beds, a desk, a chair, and a mirror.

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
2.5 star property
1.7 mi from Clarendon County
8.6 out of 10, Excellent, (1,003 reviews)
"Room was clean and I got peaceful rest. Plenty of room to park my truck and the breakfast was good. Definitely a good deal price wise and updated amenities."
$82 nightly
The price is $91
Nov 22 - Nov 23
Total with taxes and fees
SureStay Hotel by Best Western Manning
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See all properties in Clarendon County
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.